CME Empowerment Series 2021

Cervical Cancer – From Screening to Treatment

Cervical cancer is the second most common cancer in women worldwide, and is now the 10th commonest women’s cancer in Singapore. The incidence here has decreased over the years due to improved economic status, improved screening and treatment of precancerous disease. This CME talk will focus on cervical cancer. A general overview will be presented, with discussion on improved cervical cancer screening test with Pap smear and HPV test. There will also be discussion on recent advances in treatment in cervical cancer.

Speakers

Dr Wong Chiung Ing

Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Lisa Wong

Senior Consultant, Gynaecological Oncologist
Lisa Wong Women & Gynae Oncology Centre

Advances in Lung Cancer Diagnosis & Management

Lung cancer is one of the commonest cancer in both men and women. In the past, prognosis was uniformly poor. Treatment options were limited with survival less than 1 year for most patients with advanced disease. But with the development of personalised medicine, targeted therapy and immunotherapy, survival of patients has increased many fold. This significant improvement in survival outcomes is primarily due to an improved genetic characterisation of lung cancer as well as development of new targeted and immunotherapy, so much so that lung cancer is no longer just small cell vs non-small cell lung cancer but rather a heterogeneous group of diseases driven by a wide range of cancer oncogenes. As part of our multi-disciplinary CME webinar series, we invite 2 experts to discuss this complex topic with the pathologist reviewing the pathological workup of lung cancer followed by the medical oncologist to share on the latest updates in lung cancer treatment.

Speakers

Dr Chin Tan Min

Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Brendan Pang

Consultant, Pathologist
ParkwayHealth Laboratory

Covid-19 : An Update on the Pandemic Situation and its Impact on Cancer Patients

COVID19 has completely turned the world upside down. Since its first identification in Wuhan China in Dec 2019, COVID19 has spread around the world, affecting millions and taken the lives of hundreds of thousands of people. It is a generational crisis and its full medical, economic and human behavioural impact remains unclear. In this crisis, we witnessed healthcare workers and patients being deeply impacted by the pandemic. One group in particular are cancer patients. Cancer patients require frequent lifesaving chemotherapy and surgery, which weakens their immune system, predisposing them to more severe complications should they catch the COVID19. Five months into the crisis, it is timely for us to evaluate the data, update on the COVID19 pandemic situation, examine the impact on cancer patients and anticipate the challenges that lay ahead of us.

Speakers

Dr Richard Quek

Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Wong Sin Yew

Infectious Disease Physician
Infectious Disease Specialists™

Parkway Cancer Centre Tumour Board

Parkway Cancer Centre(PCC) Tumour Board is a multi-disciplinary discussion platform where unusual or challenging oncology cases are presented for discussion. After each case presentation, we have a live interactive review of the radiology images and pathology slides by the respective experts. This is followed by an in-depth discourse of each case. To enhance the learning experience of all participants, we incorporate a short commentary on a particular interesting aspect of each case to be given by the presenter. Typically, 3-4 cases would be presented at each meeting.

Speakers

Dr Richard Quek

Chairperson of PCC Tumour Board
Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Peter Goh

Senior Consultant, Diagnostics Radiologist
Mount Elizabeth Hospital

Dr Brendan Pang

Consultant, Pathologist
ParkwayHealth Laboratory

Systemic Therapy for Advanced/Unresectable Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, and the burden of this cancer is expected to increase further in the coming years. Most patients with newly diagnosed with HCC are not candidates for curative treatment because of gross vascular invasion, extrahepatic metastases and/or poor liver function, highlighting the importance of systemic therapy. While the past decade has seen a paradigm shift in systemic treatment for HCC toward molecular targeted therapy, many unmet needs remain. This presentation will review the current role of molecular targeted therapy as well as immunotherapy for HCC and offer some insight to what the future may hold for the systemic treatment of this cancer.

Speakers

Dr Zee Ying Kiat

Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Eugene Liu

Consultant, Radiologist
Parkwayhealth Radiology

Update on Cancer Pain Management

Cancer pain is a common symptom faced by cancer patients. Family physicians and specialists who are looking after cancer patients will need to be familiar with cancer pain management and the use of common analgesia. This talk will provide an update on the newer analgesia available in Singapore and also a brief on how difficult cancer pain is managed in the hospital setting.

Speakers

Dr Kok Jaan Yang

Senior Consultant, Palliative Medicine
Parkway Cancer Centre

Dr Tan Tee Yong

Consultant, Anaesthesiologist
Integrative Pain Centre

What’s New in Nasopharyngeal Cancer

Nasopharyngeal cancer remains an important cancer regionally, even as mortality rates in Singapore and elsewhere are trending downwards. We review recent advances in diagnosis and treatment which have improved cure rates. We also look at current and future efforts to improve therapy whist reducing toxicities. 1. NPC – An “Asian” disease? 2. Imaging & patterns of spread 3. Current radiation therapy techniques 4. How to mitigate acute & late toxicities? 5. How to manage local recurrences 6. Concurrent chemotherapy with radiation in local disease 7. Role of induction chemotherapy in local disease 8. Systemic treatment in advanced NPC – chemotherapy, targeted therapy and immunotherapy 9. Looking ahead ….

Speakers

Dr Lim Hong Liang

Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Ivan Tham

Senior Consultant, Radiation Oncologist
Parkway Cancer Centre

Haematological Malignancies Identified on the Full Blood Count

The Full Blood Count (FBC) is one of the commonest tests performed in everyday clinical practice. Various abnormalities are often seen on FBC results. Sometimes, these abnormalities are a manifestation of an underlying haematological malignancy. This CME talk will focus on FBC results of patients presenting with various types of haematological cancers. We will also look at what happens after patients are referred and how they are treated.

Speakers

Dr Colin Phipps Diong

Senior Consultant, Haematologist
Parkway Cancer Centre

Parkway Cancer Centre Tumour Board

Parkway Cancer Centre (PCC) Tumor Board is a multi-disciplinary discussion platform where unusual or challenging oncology cases are presented for discussion. Following each case presentation, we have a live interactive review of the radiology images and pathology slides by the respective experts, followed by an in-depth discourse of each case. To enhance the learning experience for all participants, we incorporate a short commentary on a particular interesting aspect of each case to be given by the presenter. Three cases will be presented at this upcoming session: a) Challenging case of breast cancer b) Immunotherapy in solid organ transplant patient c) Cardiac amyloidosis secondary to myeloma

Speakers

Dr Richard Quek

Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Peter Goh

Senior Consultant, Diagnostics Radiologist
Mount Elizabeth Hospital

Dr Brendan Pang

Consultant, Pathologist
ParkwayHealth Laboratory

Large B-Cell Lymphoma – Different Presentations and Treatments of the Commonest Lymphoma

Diffuse large B-cell lymphoma (DLBCL) is the commonest type of lymphoma. In the last two decades there has been an increasing recognition of the different subtypes of DLBCL and how these subtypes differ in presentation, prognosis, and treatment. In this presentation, we will look at a few cases that illustrate the different DLBCL subtypes and how novel agents beyond chemotherapy are shaping treatment paradigms.

Speakers

Dr Lee Yuh Shan

Senior Consultant, Haematologist
Parkway Cancer Centre

Dr Colin Phipps Diong

Senior Consultant, Haematologist
Parkway Cancer Centre

Understanding Metastatic Colorectal Cancer

Colorectal cancer is one of the most common cancers globally. Besides an ageing population and the dietary habits of high-income countries, factors such as obesity, lack of physical exercise, and smoking increase the risk of colorectal cancer. Advancements in pathophysiological understanding as well as molecular biology have increased the array of treatment options for advanced disease. These includes targeted and immunotherapy on top of chemotherapy. These new treatment options have improved median overall survival for advanced disease to approximately 3 years compared 6 to 9 months without treatment at all.

Speakers

Dr Foo Kian Fong

Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Brendan Pang

Consultant, Pathologist
ParkwayHealth Laboratory

Breast Cancer : Advances Made in The Last 30 Years of Care

The diagnosis and management of breast cancer have changed dramatically over the past decades in response not only to technological advances but also to cultural and social aspects of the disease. As systemic therapies for breast cancer progress in precision, radical surgical approaches for the breast and the axilla de-escalate. A multidisciplinary approach is of paramount importance from diagnosis and biopsy options to timing of surgery and irradiation; neoadjuvant or adjuvant systemic therapies and continued surveillance.

Speakers

Dr Khoo Kei Siong

Deputy Medical Director and Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Esther Chuwa

Breast Surgeon & Medical Director
Esther Chuwa BreastCare Breast Clinic

Onco-Cardiology: Cardiovascular Toxicities of Cancer and its Contemporary Treatment

Onco-cardiology is a rapidly developing new field focused on the impact of cancer and anti-cancer treatment on the human cardiovascular system. Essentially all anti-cancer agents are associated in some ways to development of cardiotoxicity, which can be divided into broadly including direct cytotoxic effects of chemotherapy and associated cardiac systolic dysfunction, cardiac ischemia, arrhythmias, and inflammatory changes of myocarditis/pericarditis. In this PCC CME webinar, we aim to highlight the different classes of common anti-cancer drugs that may pre-dispose a patient to cardio-toxicities, and expand on the diagnosis, management and follow-up of cancer patients who develop, or at risk of developing, the various forms of cardio-toxicities.

Speakers

Dr Richard Quek

Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Jeremy Chow

Cardiologist & Physician Electrophysiologist & Certified Cardiac Device Specialist
Asian Heart & Vascular Centre

Parkway Cancer Centre Tumour Board

Parkway Cancer Centre(PCC) Tumour Board is a multi-disciplinary discussion platform where unusual or challenging oncology cases are presented for discussion. After each case presentation, we have a live interactive review of the radiology images and pathology slides by the respective experts. This is followed by an in-depth discourse of each case. To enhance the learning experience of all participants, we incorporate a short commentary on a particular interesting aspect of each case to be given by the presenter. Typically, 3-4 cases would be presented at each meeting.

Speakers

Dr Richard Quek

Chairperson of PCC Tumour Board
Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Peter Goh

Senior Consultant, Diagnostics Radiologist
Mount Elizabeth Hospital

Dr Brendan Pang

Consultant, Pathologist
ParkwayHealth Laboratory

Advancing Breast Cancer Treatment by Minimising Toxicities of Chemotherapy and Radiation

An update for General Practitioners and Non Oncologists on the Role of Hormones in Breast cancer; its therapeutic manipulation and role in early and advanced breast cancer; and the recent advances in therapeutic radiation in minimising toxicities. Dr See Hui Ti will share on the discovery of Female Hormones and its role in breast cancer; followed by the historical and recent development of therapeutic anti-hormone manipulation in both early and advanced breast cancer from 1950s to 2020. She will also discuss how one determines the appropriateness of treatment. Dr Lee Kuo Ann will share on the advancement in the role of therapeutic radiation in management of breast cancer.

Speakers

Dr See Hui Ti

Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Lee Kuo Ann

Senior Consultant, Radiation Oncologist
Parkway Cancer Centre

Ovarian Mass: Evaluation, Diagnosis & Management

Ovarian masses are common amongst pre and postmenopausal women. These can range from benign causes such ovarian cysts, fibromas and cystadenoma, to malignant causes such as ovarian cancer, germ cell tumours and sex cord stromal tumours. Ovarian cancer is the eighth most common cause of women’s cancer worldwide, resulting in 200,000 deaths per year.

This CME talk will focus on evaluation of ovarian masses. A general overview of the causes, symptoms, evaluation and management will be discussed. An update of the treatment of ovarian cancer will also be presented.

Speakers

Dr Wong Chiung Ing

Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Chia Yin Nin

Senior Consultant, Gynaecological Oncologist
Gynaecology & Oncology Specialists

Lung Cancer: Screening & Early Stage Treatment

Lung cancer is the leading cause of cancer-related mortality worldwide. In Singapore, lung cancer is the most common cause of cancer deaths among men, and the second most common cause (after breast cancer) among women. More than 60% of lung cancers are diagnosed in the late stages, resulting in worse outcomes for patients. However, early stage lung cancer has a better prognosis and is potentially curative.

Previous studies had shown that screening with chest x-rays does not reduce the mortality rate from lung cancer. Currently, low-dose computed tomography (LDCT) is the only recommended screening strategy for lung cancer.

This talk will focus on screening strategies for lung cancer, and discuss treatment options for early stage lung cancer.

Speakers

Dr Chin Tan Min

Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Ng Yuen Li

Consultant Radiologist
ParkwayHealth Radiology

Parkway Cancer Centre SARCOMA Tumour Board

Parkway Cancer Centre (PCC) Tumor Board is a multi-disciplinary discussion platform where unusual or challenging oncology cases are presented for discussion. Following each case presentation, we have a live interactive review of the radiology images and pathology slides by the respective experts, followed by an in-depth discourse of each case. To enhance the learning experience for all participants, we incorporate a short commentary on a particular interesting aspect of each case to be given by the presenters.

In this upcoming Tumor Board, we focus on the topic of bone and soft tissue sarcoma.

Five cases would be presented at this upcoming session:
a) Tibial osteosarcoma by Dr Gurpal Singh
b) Pelvic Ewing’s sarcoma by Dr Suresh Nathan
c) Gluteal liposarcoma by Dr Leon Foo
d) Abdominal Desmoplastic Small Round Cell Tumor by Dr Melissa Teo
e) Paediatric Rhabdoid Tumor by Dr Anselm Lee

Speakers

Dr Richard Quek

Chairperson of PCC Tumour Board
Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Peter Goh

Senior Consultant, Diagnostics Radiologist
Mount Elizabeth Hospital

Dr Brendan Pang

Consultant, Pathologist
ParkwayHealth Laboratory

Colorectal Cancer: Protect, Detect & Resect

These are unprecedented times. Amidst this pandemic, we must not forget that Cancer still remains the top killer in Singapore, with Colorectal Cancer being the most common locally.

Colorectal cancer is the most common cancer amongst males and second in females, with more than 1,900 new cases diagnosed annually here. Despite advances in detection and treatment strategies, majority of cases are still diagnosed late.

This presentation will address the key preventive strategies and screening methods for colorectal cancer. It will also highlight the latest surgical treatments, including laparoscopic and robotic surgery, which have helped to improve outcomes for patients.

Speakers

Dr Foo Kian Fong

Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Mark Wong

Senior Consultant, General & Colorectal Surgeon
Mark Wong Surgery

Localised Prostate Cancer: Surgery or Radiation?

Prostate cancer is currently the 3rd most common cancer amongst men in Singapore, and the incidence has been rising sharply in recent years.

At the same time, advances in surgery, radiation therapy and systemic therapy have improved cure rates or reduced side effects for our patients.This webinar will focus on the two main treatment modalities for localised prostate cancer – surgery and radiation therapy.

Dr Colin Teo, a urologist, will discuss on curative Robotic Surgery for localized prostate cancer with techniques minimizing functional morbidity of urinary incontinence and erectile dysfunction

Dr Ivan Tham, a radiation oncologist, will discuss when radiation therapy would be appropriate, and how it can be delivered safely to maximise cure whilst minimising toxicity.

Speakers

Dr Colin Teo

Senior Consultant, Urologist
Colin Teo Urology

Dr Ivan Tham

Senior Consultant, Radiation Oncologist
Parkway Cancer Centre

Parkway Cancer Centre HAEMATOLOGY Tumour Board

Parkway Cancer Centre(PCC) Tumour Board is a multi-disciplinary discussion platform where unusual or challenging oncology cases are presented for discussion.

Following each case presentation, we have a live interactive review of the radiology images and pathology slides by the respective experts, followed by an in-depth discourse of each case.

To enhance the learning experience for all participants, we incorporate a short commentary on a particular interesting aspect of each case to be given by the presenter.

Three cases will be presented at this upcoming session:
a) Multiple Myeloma with retroperitoneal fibrosis and adenocarcinoma of the stomach
b) MALT lymphoma of the eye
c) Secondary Central Nervous system lymphoma with colonic polyp

Speakers

Dr Lee Yuh Shan

Chairperson of PCC Tumour Board
Senior Consultant, Haematologist
Parkway Cancer Centre

Dr Peter Goh

Senior Consultant, Diagnostics Radiologist
Mount Elizabeth Hospital

Dr Brendan Pang

Consultant, Pathologist
ParkwayHealth Laboratory

Parkway Cancer Centre GASTROINTESTINAL Tumour Board

Parkway Cancer Centre(PCC) Tumour Board is a multi-disciplinary discussion platform where unusual or challenging oncology cases are presented for discussion.

Following each case presentation, we have a live interactive review of the radiology images and pathology slides by the respective experts, followed by an in-depth discourse of each case.

To enhance the learning experience for all participants, we incorporate a short commentary on a particular interesting aspect of each case to be given by the presenter.

In this Tumour Board, we focus on the topic of gastrointestinal cancers.

Three cases will be presented at this upcoming session:
a) Intra-hepatic Cholangiocarcinoma discussing the selection of cases for surgery and the role of adjuvant chemotherapy
by Dr Liau Kui Hin and Dr Foo Kian Fong

b)Low Rectal cancer discussing the role of neoadjuvant chemoradiotherapy and sphincter sparing surgical procedures
by Dr Dean Koh and Dr Foo Kian Fong

c) Gastric cancer discussing the role of neoadjuvant chemotherapy
by Dr Zee Ying Kiat

(KIV) Metastatic HER2-positive gallbladder carcinoma
by Dr Richard Quek

Speakers

Dr Foo Kian Fong

Chairperson of PCC Tumour Board
Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Peter Goh

Senior Consultant, Diagnostics Radiologist
Mount Elizabeth Hospital

Dr Brendan Pang

Consultant, Pathologist
ParkwayHealth Laboratory

Parkway Cancer Centre GENITOURINARY Tumour Board

Parkway Cancer Centre(PCC) Tumour Board is a multi-disciplinary discussion platform where unusual or challenging oncology cases are presented for discussion.

Following each case presentation, we have a live interactive review of the radiology images and pathology slides by the respective experts, followed by an in-depth discourse of each case.

To enhance the learning experience for all participants, we incorporate a short commentary on a particular interesting aspect of each case to be given by the presenter.

In this Tumour Board, we focus on the topic of genitourinary cancers.

Three cases will be presented at this upcoming session:
a) Management of Mediastinal Non Seminomatous Germ Cell Tumor (NSGCT) with Bleomycin toxicity,
Presenter: Dr Richard Quek, Discussant: Dr Tan Aik Hau.

b) Metastatic renal cell carcinoma after failing first-line targeted therapy,
Presenter: Dr Ang Peng Tiam, Discussant: Dr Zee Ying Kiat.

c) Metastatic prostate cancer with disease progression after multiple lines of treatment,
Presenter: Dr Ang Peng Tiam, Discussant: Dr Tan Yeh Hong and Dr Ong Seng Chuan.

Speakers

Dr Khoo Kei Siong

Chairperson of PCC Tumour Board
Deputy Medical Director & Senior Consultant, Medical Oncologist
Parkway Cancer Centre

Dr Peter Goh

Senior Consultant, Diagnostics Radiologist
Mount Elizabeth Hospital

Dr Brendan Pang

Consultant, Pathologist
ParkwayHealth Laboratory

Parkway Cancer Centre Tumour Board & Oncology Update

Parkway Cancer Centre (PCC) Tumour Board is a multi-disciplinary discussion platform where unusual or challenging oncology cases are presented for discussion. To enhance the learning experience for all participants, we incorporate an oncology update.

For this session, the oncology update will focus on Mucosal Melanoma, to be presented by Dr Richard Quek, where he will provide a succinct overview on the challenges associated with the management of mucosal melanomas.

Speakers

Dr Richard Quek

Chairperson of PCC Tumour Board
Senior Consultant
Medical Oncology
Parkway Cancer Centre

Dr Peter Goh

Senior Consultant, Diagnostics Radiologist
Mount Elizabeth Hospital

Dr Brendan Pang

Consultant, Pathologist
ParkwayHealth Laboratory

Pregnancy and Breast Cancer

Breast Cancer in general is the commonest cancer in women, and there is a trend towards a younger age. Conversely there is also a trend in childbearing in older women. What can one do when one gets diagnosed with breast cancer during pregnancy?

Understand the considerations of management of cancer in ladies of child bearing age and during pregnancy in this webinar.

Speakers

Dr See Hui Ti

Senior Consultant
Medical Oncology
Parkway Cancer Centre

Tumour Board & Oncology Update

Parkway Cancer Centre (PCC) Tumour Board is a multi-disciplinary discussion platform where unusual or challenging oncology cases are presented for discussion. To enhance the learning experience for all participants, we incorporate an oncology update.

For this session, the oncology update will focus on Head & Neck Cancer, to be presented by Dr Tan Ngian Chye.

Speakers

Dr Richard Quek

Senior Consultant
Medical Oncology
Parkway Cancer Centre

Dr Peter Goh

Senior Consultant
Diagnostics Radiologist
Mount Elizabeth Hospital

Dr Brendan Pang

Consultant
Pathologist
ParkwayHealth Laboratory

Dr Tan Ngian Chye

Senior Consultant
Head & Neck and General Surgeon
Mount Elizabeth Novena Hospital

Dr Benjamin Chua Soo Yeng

Medical Director & Senior Consultant
Vascular & Endovascular Surgeon General Surgery
Mount Elizabeth Novena Hospital